The terminal half-life [ t12 ] is rather long at 25 hours and constant plasma levels [ Css ] are only reached after more than hours. The protein binding [ Pb ] is About The metabolism mainly takes place via CYP3A4. Recommendation: The risk of a serotonergic syndrome is increased, but without an exact answers to the cognitive, vegative and neuromuscular symptom questions we cannot make any recommendations for action.
Rating: Duloxetine and phentermine modulate the serotonergic system to a moderate extent. Rating: According to our knowledge, phentermine does not increase anticholinergic activity. The anticholinergic effect of duloxetine is not relevant. We do not know of any QT-prolonging potential for duloxetine and phentermine. Metabolic Weight loss: duloxetine. Musculoskeletal Musculoskeletal pain: duloxetine.
Neurological Dizziness: duloxetine Dream disorder: duloxetine Paresthesia: duloxetine Tremor: duloxetine Cerebrovascular accident: phentermine.
Systemic Fatigue: duloxetine. Mental Agitation: duloxetine Suicidal: duloxetine Psychosis: phentermine. Reproductive system Abnormal ejaculation: duloxetine Erectile dysfunction: duloxetine Orgasm disorder: duloxetine Reduced libido: duloxetine. Cardiac Hypertensive crisis: duloxetine Orthostatic hypotension: duloxetine Cardiomyopathy: phentermine. Dermatological Stevens johnson syndrome: duloxetine.
Electrolytes Hyperkalemia: duloxetine Hyponatremia: duloxetine. Hematological Hemorrhage: duloxetine. Hepatic Hepatotoxicity: duloxetine. Ophthalmological Glaucoma: duloxetine. Based on your answers and scientific information, we assess the individual risk of undesirable side effects. These recommendations are intended to advise professionals and are not a substitute for consultation with a doctor.
In the restricted test version alpha , the risk of all substances has not yet been conclusively assessed. Intended use Explanations of the substances for patients.
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